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Pro Catfish Expedition on Santee Cooper Lakes

  • Published Date: September 11, 2025
  • Fishing
  • Santee Cooper
  • $400 - $450 price range

Summary

Get ready for a full day of serious catfishing on the Santee Cooper Lakes with Tight Line Therapy. This 8-hour guided trip is tailored for professional anglers looking to target big Blue and Channel Catfish in Lake Marion and Lake Moultrie. Your experienced guides know these waters inside and out, and they'll put you on the most productive spots using proven techniques. You'll be using top-notch gear to increase your chances of hooking into some real trophy-sized cats. This isn't your average fishing trip – it's an intensive, expert-level experience designed to challenge even seasoned anglers. Whether you're after that personal best or just want to learn from the pros, this private charter offers a unique opportunity to up your catfish game on two of South Carolina's premier lakes.
Pro Catfish Expedition on Santee Cooper Lakes

Monster Catfish Moments

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4 people enjoying a fishing trip in SC

Fishing Success on Lake Marion

3 people fishing for 4 striped bass at Cross location

Santee Cooper Bass Fishing Day

Two anglers fishing at the Cross location

Catfish Action in South Carolina

3 striped bass caught during fishing trip in SC

Lake Moultrie Trophy Catch

Fishing trip with group of 5 people at Cross location

Family Fishing Fun in Santee Cooper

Person fishing with cross in the background

Guided Catfish Trip on Lake Moultrie

Blue catfish caught while fishing

Big Catch at Santee Cooper Lakes

Two fish caught during a fishing trip at the Cross location

South Carolina Striper Fishing

Angler with rod fishing in South Carolina

Scenic Day Fishing Lake Moultrie

Avid angler fishing in South Carolina

Catfishing with Local Guides

4 people enjoying a fishing trip in SC

Fishing Success on Lake Marion

3 people fishing for 4 striped bass at Cross location

Santee Cooper Bass Fishing Day

Two anglers fishing at the Cross location

Catfish Action in South Carolina

3 striped bass caught during fishing trip in SC

Lake Moultrie Trophy Catch

Fishing trip with group of 5 people at Cross location

Family Fishing Fun in Santee Cooper

Person fishing with cross in the background

Guided Catfish Trip on Lake Moultrie

Blue catfish caught while fishing

Big Catch at Santee Cooper Lakes

Two fish caught during a fishing trip at the Cross location

South Carolina Striper Fishing

Angler with rod fishing in South Carolina

Scenic Day Fishing Lake Moultrie

Avid angler fishing in South Carolina

Catfishing with Local Guides

4 people enjoying a fishing trip in SC

Fishing Success on Lake Marion

3 people fishing for 4 striped bass at Cross location

Santee Cooper Bass Fishing Day

Two anglers fishing at the Cross location

Catfish Action in South Carolina

3 striped bass caught during fishing trip in SC

Lake Moultrie Trophy Catch

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Santee Cooper Catfish: Pro Angler's Dream Trip

Ready to chase some whiskers on two of South Carolina's most legendary catfish lakes? Bob's Guide Service Encore has you covered with this full-day adventure on the Santee Cooper system. We're talking about Lake Marion and Lake Moultrie - a catfisherman's paradise where monster blues and chunky channels lurk in the depths. This ain't your grandpa's cane pole fishing, folks. We're going after the big boys with cutting-edge techniques and gear that'll make you feel like you've stepped onto the set of a pro fishing show.

What to Expect on the Water

Strap in for 8 solid hours of catfish action with the pros at Tight Line Therapy. This ain't no rookie run - we're talking a private charter tailored for anglers who know their stuff and want to up their game. You and a buddy will have the full attention of our seasoned guides as we hit the honey holes across both Lake Marion and Lake Moultrie. We're not messing around with dinky cats here - our target is trophy-class blue cats and channel cats that'll make your arms ache and your fishing buddies green with envy.

Don't worry about bringing a tackle box full of gear. We've got you covered with top-of-the-line equipment that's perfect for battling the bruisers of the Santee Cooper system. From specialized rods to the latest in fish-finding tech, you'll be fishing with the kind of setup that makes other anglers do a double-take at the boat ramp.

Techniques That Land Lunkers

Listen up, because this is where the magic happens. We're not just chunking chicken livers and hoping for the best. Our guides have dialed in techniques that consistently put clients on big fish. We're talking about precision drifting, strategic anchoring, and bait presentation that'll make those catfish think Christmas came early.

Depending on conditions, we might be using planer boards to cover more water, or we could be slow-trolling deep channels where the monsters hide. You'll learn how to read the lake like a pro, identifying those subtle changes in bottom structure that hold big cats. And when it comes to bait, we've got a few tricks up our sleeve that might surprise you - ever tried soap as catfish bait? You might just become a believer after this trip.

Top Catches This Season

While we don't have specific customer reviews to share, the tales from the lake this season have been nothing short of epic. Anglers have been pulling in blue cats pushing the 50-pound mark, with a few lucky souls landing true giants in the 70-80 pound range. Channel cats have been just as cooperative, with plenty of eaters in the 5-10 pound class and some real beauties topping 20 pounds. The key has been finding the right depth and structure, then presenting baits that these hungry cats just can't resist.

Species You'll Want to Hook

Blue Catfish: The undisputed king of the Santee Cooper system, blue cats in these lakes grow to monstrous proportions. We're talking about fish that can top 100 pounds, though anything over 50 is considered a true trophy. These behemoths love deep water and strong current, often hanging around underwater structure like old river channels or submerged timber. Blues are most active in the cooler months, but can be caught year-round if you know where to look. When a big blue takes your bait, hold on tight - these fish fight like freight trains and will test every bit of your angling skill.

Channel Catfish: Don't let their smaller size fool you - channel cats are pound-for-pound some of the scrappiest fighters you'll encounter. In the Santee Cooper lakes, channels commonly reach 5-15 pounds, with some topping 20 or even 30 pounds. These fish are opportunistic feeders, which means they'll hit a variety of baits and can be caught using multiple techniques. Channels tend to prefer slightly shallower water than blues, often hanging around points, creek mouths, and flats. The fight of a good-sized channel cat is something every angler should experience - they pull hard, make quick runs, and aren't afraid to use the boat to their advantage.

Why Anglers Keep Coming Back

There's a reason the Santee Cooper lakes have a reputation as one of the best catfish destinations in the country. It's not just the size of the fish - though that's certainly part of it. It's the whole package. You've got two massive lakes with diverse habitat, from shallow flats to deep channels, giving cats plenty of places to grow big and strong. The forage base is rich, which means these fish are well-fed and healthy.

But what really sets this trip apart is the expertise you're tapping into. Our guides have spent countless hours on these waters, learning the patterns and behaviors of these fish. They know when the cats are likely to be feeding shallow or when they've moved out to deeper haunts. This isn't just a fishing trip - it's a masterclass in catfish angling on some of the most productive waters in the Southeast.

Time to Book Your Spot

If you're serious about your catfishing, this is the trip you've been waiting for. Whether you're looking to land that fish of a lifetime or just want to load the cooler with some good eaters, the Santee Cooper lakes deliver. With Bob's Guide Service Encore and Tight Line Therapy, you're not just getting a guide - you're getting a partner in your pursuit of catfish glory.

Remember, this is a private charter for two anglers, so it's perfect for you and your fishing buddy to get some focused, one-on-one instruction. We don't provide meals, so make sure to pack some grub to keep your energy up for those long fights with big cats. And while we can't guarantee you'll break any records, we can promise you'll come away with new skills, great memories, and probably a few fish stories that'll be hard for your friends to believe.

Don't let another season slip by without experiencing the catfish mecca that is the Santee Cooper system. Spots fill up fast, especially during peak seasons, so don't wait to book. Get in touch with Bob's Guide Service Encore today and let's get you on the water. Those whiskers won't catch themselves, and trust me, once you've felt the pull of a Santee Cooper catfish, you'll be hooked for life. See you on the lake!

Learn more about the species

Blue Catfish

Blues are the heavyweight champs of Santee Cooper. These monsters can top 100 pounds, though 20-50 pounders are more common. Look for them in deep channels and holes, especially where tributaries meet the main lake. Blues are opportunistic feeders, gobbling up anything from baitfish to smaller catfish. They put up a serious fight, so sturdy tackle is a must. Anglers target blues for the thrill of battling a true giant. Prime time is winter through early spring when big fish move shallow to feed. For bait, nothing beats fresh cut shad or herring. Here's a pro tip: use circle hooks to improve your hookup ratio and make releases easier. Blues have become more numerous in recent years, so there's a good chance of hooking into a trophy. Just be ready for a workout - these bruisers don't give up easily!

Blue Catfish

Channel Catfish

Channel cats are the bread and butter of Santee Cooper fishing. These whisker-faced bottom feeders typically run 2-10 pounds, though 20-pounders aren't unheard of. You'll find them lurking near structure in both shallow and deep water, especially around stumps and drop-offs. They're most active at night and during overcast days. Anglers love targeting channels for their hard-fighting spirit and excellent table fare. To hook into one, try drifting cut bait or stinkbait along the bottom. A local trick is to use chicken liver marinated in garlic - the scent drives them wild. Keep your rod tip up when you feel a bite; channels have tough mouths and need a solid hookset. Spring and fall are prime seasons, but you can catch them year-round in the Santee lakes. Just be careful handling them - those fins are sharp!

Channel Catfish

About the Bob's Guide Service Encore

Company vehicle

Vehicle Guest Capacity: 6

Manufacturer Name: Yamaha

Maximum Cruising Speed: 40

Number of Engines: 1

Horsepower per Engine: 115

Ready for some serious catfishing action? Hop aboard our specialized vessel for a full day chasing monster cats on the legendary Santee Cooper Lakes. Our seasoned guides know all the prime spots on Lake Marion and Lake Moultrie where the big blues and channels lurk. We'll set you up with top-notch gear and share pro-level tactics to give you the best shot at hooking into some real whoppers. This ain't no leisurely cruise - we're talking 8 solid hours of focused fishing for those looking to up their catfish game. Whether you're aiming to break personal records or just want to learn from the experts, this private charter delivers an intensive catfishing experience tailored for serious anglers. Bring your A-game and get ready to tangle with some of the biggest cats these lakes have to offer!
Bob's Guide Service Encore

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Book a trip with Santee Cooper fishing guide now and get access to the best lake fishing around. We'll take care of all the details, including equipment and gear. Contact us today and experience an exciting, unforgettable day on the water.

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